Smith R W, Masters M, Donachie W D
Institute of Cell and Molecular Biology, University of Edinburgh, Scotland.
J Bacteriol. 1993 May;175(9):2788-91. doi: 10.1128/jb.175.9.2788-2791.1993.
For normal cell division, the ftsZ gene must be transcribed from a number of promoters that are located within the proximal upstream genes (ddlB, ftsQ, and ftsA). We show that the main promoters have identical responses to changes in growth rate, i.e., under all conditions, the frequency of transcription per septum formed is approximately constant and independent of cell size or growth rate per se. We also show that transcription from these promoters is independent of stationary-phase transcription factor sigma s.
对于正常的细胞分裂,ftsZ基因必须从位于近端上游基因(ddlB、ftsQ和ftsA)内的多个启动子进行转录。我们发现,主要启动子对生长速率变化具有相同的响应,即在所有条件下,每个形成的隔膜的转录频率大致恒定,且与细胞大小或生长速率本身无关。我们还表明,这些启动子的转录独立于稳定期转录因子σs。