Fitzpatrick R, Ziebland S, Jenkinson C, Mowat A, Mowat A
Department of Rheumatology, Nuffield Orthopaedic Centre, Oxford, UK.
J Rheumatol. 1993 Mar;20(3):429-36.
We carried out a study to compare the sensitivity to change of disease specific compared with more generic health status instruments in relation to rheumatoid arthritis (RA). A sample of 102 patients was recruited and assessed by means of 4 health status instruments and standard rheumatological measures on 3 occasions separated by 3 monthly intervals. Sensitivity to change for mobility, activities of daily living, household, pain, emotions and social dimensions were calculated. For some dimensions disease specific health status instruments performed less well. However overall there was no evidence of consistent differences between the 2 approaches. We conclude that generic instruments have a role in the assessment of RA.
我们开展了一项研究,以比较针对类风湿性关节炎(RA)的疾病特异性健康状况测量工具与更通用的健康状况测量工具在对变化的敏感性方面的差异。招募了102名患者作为样本,并通过4种健康状况测量工具和标准风湿病测量方法,在间隔3个月的3个时间点进行评估。计算了在活动能力、日常生活活动、家庭事务、疼痛、情绪和社会维度方面对变化的敏感性。对于某些维度,疾病特异性健康状况测量工具的表现较差。然而,总体而言,没有证据表明这两种方法之间存在持续的差异。我们得出结论,通用测量工具在类风湿性关节炎的评估中具有一定作用。