鳕鱼过敏原M的致敏结构。III. 长序列肽的抗原性研究。
The allergenic structure of allergen M from cod. III. Studies on the antigenicity of long-sequence peptides.
作者信息
Apold J, Elsayed S, Aukrust L, Bennich H
出版信息
Int Arch Allergy Appl Immunol. 1979;58(3):337-43. doi: 10.1159/000232210.
PMID:84803
Abstract
Fragments TM 1 (75 amino acid residues) and TM 2 (38 amino acid residues), and 3 other polypeptides (range 16-25 amino acid residues) of Allergen M from cod were shown to be active in rabbit IgG-mediated reactions. The same peptides were previously found to possess reactivity in IgE-mediated reactions, thus suggesting a structural relationship between their antigenic and allergenic determinants.
摘要
鳕鱼变应原M的片段TM 1（75个氨基酸残基）和TM 2（38个氨基酸残基），以及其他3种多肽（16 - 25个氨基酸残基）在兔IgG介导的反应中显示出活性。先前发现相同的肽在IgE介导的反应中具有反应性，因此表明它们的抗原决定簇和变应原决定簇之间存在结构关系。
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