Gorcsan J, Lazar J M, Romand J, Pinsky M R
Department of Medicine, University of Pittsburgh, PA.
Am Heart J. 1993 May;125(5 Pt 1):1316-23. doi: 10.1016/0002-8703(93)91001-u.
Echocardiographic automated border detection (ABD) is a new on-line technique that can determine the interface between blood and myocardial tissue and calculate left ventricular (LV) cavity area in real time. The objective of this study was to determine whether ABD measurements of the LV cavity area could be used to estimate LV stroke volume at basal conditions and during large changes in LV stroke volume induced by inferior vena caval occlusions in an open-chest canine model. Seven dogs had LV stroke volume measured by electromagnetic flow from the ascending aorta with epicardial recordings of ABD echocardiographic area at the midventricular short-axis level. Simultaneous beats of stroke volume were recorded along with ABD echo area during baseline apnea and during IVC occlusions. Neither ABD echo stroke area nor stroke volume varied significantly during apnea baseline. Changes in stroke area were closely correlated with changes in stroke volume for 540 matched beats from 24 IVC occlusions: R = 0.93, standard error of the estimate = 5%, y = 0.92x + 0.4 (p < 0.001). Echocardiographic ABD appears to be a promising new on-line method of determining rapid alterations in LV stroke volume; it also has potential applications to multiple investigational and clinical settings.
超声心动图自动边界检测（ABD）是一种新型在线技术，可实时确定血液与心肌组织之间的界面并计算左心室（LV）腔面积。本研究的目的是确定在开胸犬模型中，LV腔面积的ABD测量值是否可用于估计基础状态下以及下腔静脉阻塞引起的LV每搏量大幅变化期间的LV每搏量。七只犬通过电磁流量计测量升主动脉的LV每搏量，并在心外膜记录心室短轴水平的ABD超声心动图面积。在基线呼吸暂停期间和IVC阻塞期间，同时记录每搏量与ABD回声面积。在呼吸暂停基线期间，ABD回声每搏面积和每搏量均无显著变化。来自24次IVC阻塞的540对匹配搏动中，每搏面积的变化与每搏量的变化密切相关：R = 0.93，估计标准误差 = 5%，y = 0.92x + 0.4（p < 0.001）。超声心动图ABD似乎是一种很有前景的新型在线方法，可用于确定LV每搏量的快速变化；它在多种研究和临床环境中也具有潜在应用价值。
