Seidel H
Federal Institute for Occupational Health, Berlin, Federal Republic of Germany.
Am J Ind Med. 1993 Apr;23(4):589-604. doi: 10.1002/ajim.4700230407.
The problem of a "vibration disease" caused by low-frequency whole-body vibration (wbv) is critically discussed. Disorders of the nervous, circulatory, and digestive systems are interpreted not to be predominantly wbv-specific, but to be related to the totality of working conditions. Long-term wbv exposure can probably contribute to the pathogenesis of disorders of female reproductive organs (menstrual disturbances, anomalies of position) and disturbances of pregnancy (abortions, stillbirths). Animal experiments suggest harmful effects on the fetus. WBV has a minor synergistic effect on the development of noise-induced hearing loss. Degenerative changes of the spine are more prevalent among wbv-exposed workers. Model calculations demonstrate an increased spinal load in pregnant women exposed to wbv or self-induced vibration, and illustrate a possibility for the comparison of data on stress, strain, and strength. The analysis of individual exposure-effect relationships is suggested as a future approach for evaluating potential occupation-related diseases.
对由低频全身振动（wbv）引起的“振动病”问题进行了批判性讨论。神经、循环和消化系统的紊乱并非主要由wbv特异性引起，而是与工作条件的整体情况有关。长期暴露于wbv可能会导致女性生殖器官疾病（月经紊乱、位置异常）和妊娠障碍（流产、死产）的发病机制。动物实验表明对胎儿有有害影响。wbv对噪声性听力损失的发展有轻微的协同作用。在暴露于wbv的工人中，脊柱的退行性变化更为普遍。模型计算表明，暴露于wbv或自我诱发振动的孕妇脊柱负荷增加，并说明了比较应力、应变和强度数据的可能性。建议将个体暴露-效应关系分析作为评估潜在职业相关疾病的未来方法。
