Gothard T W, Agapitos P J, Bowers R A, Mma S, Chen V, Lindstrom R L
University of Minnesota, School of Medicine, Department of Ophthalmology, Minneapolis.
Refract Corneal Surg. 1993 Jan-Feb;9(1):51-7.
High amounts of myopia can frequently produce anisometropia and limit visual rehabilitation by conventional means in eyes with clear corneal grafts. This condition is frequently coupled with large amounts of astigmatism. Four-incision radial keratotomy provides a way to reduce myopia in normal individuals. In our present study, we used the technique of four- incision radial keratotomy to reduce myopia in a group of keratoplasty patients who failed conventional visual rehabilitation. Arcuate or transverse keratotomy was used in conjunction with radial keratotomy in eyes with high amounts of astigmatism.
This study retrospectively examined a group of 11 eyes with penetrating keratoplasty which underwent four-incision radial keratotomy for the treatment of visually disabling myopia. The radial incisions were placed in the graft, inside the graft-host interface. Seven eyes underwent concomitant arcuate relaxing incisions at the graft-host interface for treatment of associated astigmatism. One additional eye had paired straight transverse incisions for the treatment of astigmatism. The mean postoperative follow up was 16 months (range, 3 months to 5 years).
There was a mean reduction of the spherical equivalent refraction of 3.48 diopters (D) (range, 0.25 to 7.75 D). The eight eyes undergoing astigmatic surgery showed a mean reduction in keratometric astigmatism of 2.25 D (range, -6.75 to +6.50 D) and refractive astigmatism of 4.63 D (range, -1.50 to -9.50 D). Nine of the 11 eyes had stable or improved best spectacle corrected visual acuity. Two eyes had reduction of best spectacle corrected visual acuity--one due to development of irregular astigmatism and one due to worsening of preexisting macular edema.
Four-incision radial keratotomy can reduce myopia after penetrating keratoplasty when the patient is unable to tolerate spectacle or contact lens correction. It can be combined with relaxing incisions or transverse keratotomy to reduce astigmatism. There is a high amount of variability, and predictability is currently limited by the complex topographical changes occurring in corneal transplants. Complex corneal biomechanical changes may predispose these eyes to the development of irregular astigmatism.
高度近视常导致屈光参差,并限制透明角膜移植眼通过传统方法进行视力康复。这种情况常伴有大量散光。四切口放射状角膜切开术为降低正常人的近视提供了一种方法。在本研究中,我们采用四切口放射状角膜切开术,对一组常规视力康复失败的角膜移植患者降低近视度数。对于散光度数较高的眼睛,在放射状角膜切开术的同时联合使用弧形或横向角膜切开术。
本研究回顾性分析了一组11只穿透性角膜移植眼,这些眼睛接受了四切口放射状角膜切开术以治疗致盲性近视。放射状切口位于移植片内,在移植片与宿主界面内部。7只眼睛在移植片与宿主界面同时进行了弧形松解切口以治疗相关散光。另外1只眼睛进行了成对的直线横向切口以治疗散光。术后平均随访时间为16个月(范围为3个月至5年)。
等效球镜度平均降低3.48屈光度(D)(范围为0.25至7.75 D)。接受散光手术的8只眼睛角膜曲率散光平均降低2.25 D(范围为 -6.75至 +6.50 D),屈光性散光平均降低4.63 D(范围为 -1.50至 -9.50 D)。11只眼睛中有9只最佳矫正视力稳定或提高。2只眼睛最佳矫正视力下降——1只因出现不规则散光,另1只因原有黄斑水肿加重。
当患者无法耐受眼镜或隐形眼镜矫正时,四切口放射状角膜切开术可降低穿透性角膜移植术后的近视度数。它可与松解切口或横向角膜切开术联合使用以降低散光。存在高度变异性,目前可预测性受到角膜移植中发生的复杂地形变化的限制。复杂的角膜生物力学变化可能使这些眼睛易患不规则散光。