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[角膜缘平行角膜切开联合压迫缝线治疗穿透性角膜移植术后高度散光:矢量分析与地形图研究]

[Limbus-parallel keratotomies with compression sutures in treatment of high astigmatism after perforating keratoplasty: a vector analysis and topographic study].

作者信息

Vilchis E, Seitz B, Langenbucher A, Küchle M, Kus M M, Naumann G O

机构信息

Augenklinik mit Poliklinik, Universität Erlangen, Nürnberg.

出版信息

Klin Monbl Augenheilkd. 1997 Sep;211(3):151-8. doi: 10.1055/s-2008-1035115.

Abstract

BACKGROUND

Visual acuity following penetrating keratoplasty is frequently limited by excessive astigmatism which cannot be compensated for with spectacles or contact lenses. The purpose of the study was to determine the effects of arcuate keratotomies and compression sutures on the amount and regularity of corneal astigmatism and on the visual acuity.

PATIENTS AND METHODS

Between June 1989 and August 1995, 56 eyes from 56 patients (30 women, 26 men, average age 53 +/- 16 years) with excessive post-penetrating keratoplasty astigmatism were treated with paired arcuate cuts and compression sutures 4.8 +/- 3.5 years after suture removal (45% keratoconus, 30% scars, 20% dystrophies). The incisions were made along the meridian of maximum dioptric power in a sector extending for 60 +/- 15 degrees (6 mm diameter). Incision depth was standardized at 450 microns. Compression sutures were placed 90 degrees away in the flat meridian. Eight patients required more than one procedure to obtain the desired effect. Best corrected visual acuity (VA), keratometric readings and topographic power maps were analyzed pre- and postoperatively. We categorized the topographic maps into six groups: from group 1 (regular) to group 6 (irregular). For description of the astigmatic change after surgery, the formulas by Naylor and Jaffe (vector-corrected astigmatism) were applied.

RESULTS

The mean preoperative astigmatism was 10.8 +/- 3.1 (4.2 to 19.2) diopters (D). After a mean follow-up of 1.1 years, the mean net astigmatism was 5.8 +/- 3.2 (0 to 16) D. The mean preoperative visual acuity (VA) was 0.38 +/- 0.31 (from 0.03 to 1.0). At the end of follow-up, the mean VA was 0.43 +/- 0.25. Non-refractive reasons for poor visual acuity included amblyopia (n = 5), macular degeneration (n = 4), glaucoma (n = 4), cataract (n = 2), and others (n = 5). Twenty-seven percent of the preoperative topographic maps were categorized into groups 1 and 2 and only 10% into groups 5 and 6. At the end of the follow-up, none of the 53 available topographic maps was categorized into group 1, 7.5% into group 2 and 30% into groups 5 and 6. The mean astigmatic change (vector-corrected astigmatism) was 12.3 +/- 5.2 (1.0 to 29.8) D with a turn of the axes ranging from -39 to 44 degrees.

CONCLUSIONS

Arcuate incisions with compression sutures are easily performed and hold a low complication rate in comparison with other refractive operations. Definition of successful surgery is even broader when a significant reduction of astigmatism that usually allows the use of spectacles or contact lenses is considered. A disadvantage is that each particular case is unpredictable because of the tendency of the topography to irregularity and possible regression of the effect.

摘要

背景

穿透性角膜移植术后的视力常常受到严重散光的限制,而这种散光无法通过眼镜或隐形眼镜来矫正。本研究的目的是确定弧形角膜切开术和压迫性缝线对角膜散光量、规则性以及视力的影响。

患者与方法

在1989年6月至1995年8月期间,对56例患者(30例女性,26例男性,平均年龄53±16岁)的56只眼进行了治疗,这些患者在穿透性角膜移植术后存在严重散光,在拆除缝线后4.8±3.5年接受了配对的弧形切口和压迫性缝线治疗(圆锥角膜占45%,瘢痕占30%,营养不良占20%)。切口沿着最大屈光力子午线在一个延伸60±15度(直径6毫米)的扇形区域内进行。切口深度标准化为450微米。压迫性缝线在扁平子午线90度处放置。8例患者需要进行不止一次手术以获得理想效果。对术前和术后的最佳矫正视力(VA)、角膜曲率读数和地形图屈光力进行了分析。我们将地形图分为六组:从第1组(规则)到第6组(不规则)。为描述手术后的散光变化,应用了Naylor和Jaffe的公式(矢量矫正散光)。

结果

术前平均散光为10.8±3.1(4.2至19.2)屈光度(D)。平均随访1.1年后,平均净散光为5.8±3.2(0至16)D。术前平均视力(VA)为0.38±0.31(从0.03至1.0)。随访结束时,平均视力为0.43±0.25。视力不佳的非屈光性原因包括弱视(n = 5)、黄斑变性(n = 4)、青光眼(n = 4)、白内障(n = 2)以及其他(n = 5)。术前27%的地形图属于第1组和第2组,仅有10%属于第5组和第6组。随访结束时,53份可用地形图中没有一份属于第1组,7.5%属于第2组,30%属于第5组和第6组。平均散光变化(矢量矫正散光)为12.3±5.2(1.0至29.8)D,轴的旋转范围为 -39至44度。

结论

与其他屈光手术相比,弧形切口加压迫性缝线操作简便,并发症发生率低。当考虑到散光显著降低通常允许使用眼镜或隐形眼镜时,成功手术的定义更为宽泛。一个缺点是,由于地形图有不规则的趋势以及效果可能会消退,每个具体病例都难以预测。

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