Fournier D, Mercier P, Pouplard F, Menei P, Guy G
Service de Neurochirurgie, Centre Hospitalier Régional et Universitaire, Angers, France.
Childs Nerv Syst. 1993 Feb;9(1):28-31; discussion 31-2. doi: 10.1007/BF00301932.
The authors report the case of a 2-year-old baby girl with an intradural meningotheliomatous meningioma of the cauda equina which recurred three times. Despite four operative procedures and localized radiotherapy, the lesion kept on growing to reach the retroperitoneal space. Extensive laminectomy and associated radiotherapy were probably responsible for a spinal dislocation which had to be operated on. The child was left paraplegic with major bladder dysfunction after all procedures. This is the first reported case of well-documented "malignant" evolution of a spinal meningioma.
作者报告了一例2岁女婴病例,其患有马尾神经鞘膜瘤,已复发三次。尽管进行了四次手术及局部放疗,病变仍持续生长并蔓延至腹膜后间隙。广泛椎板切除术及相关放疗可能导致了脊柱脱位,不得不再次进行手术。经过所有治疗后,患儿遗留截瘫及严重膀胱功能障碍。这是首例有充分文献记载的脊髓膜瘤“恶性”进展病例。