Fortuna A, Nolletti A, Nardi P, Caruso R
Acta Neurochir (Wien). 1981;55(3-4):329-41. doi: 10.1007/BF01808449.
The literature on spinal neurinomas (N) and meningiomas (M) in children is reviewed, and five personal cases of N are added (one in the context of Recklinghausen's disease). The cases of N totalled 151, and of M 69, accounting respectively for 10.9% and 4.3% of childhood spinal tumours and 2.6% and 1.3% of spinal N and M of all ages. Sixty-one cases of N (16 in the context of Recklinghausen's disease) and 26 cases of M (5 in the context of Recklinghausen's disease) are analyzed in detail. N occurs chiefly between ages 9 and 15 years, the sex ratio is 3 : 2, all levels of the spinal canal are equally affected, and extradural N or conditions with an extradural component (48%) are more frequent than in adults (26.9%). M occurs chiefly between 12 and 15 years, the sex ratio is 3 : 2, the prevalence of the thoracic segment (47.8%) is less marked than in adults (81%), and the frequency of the extradural site (10.6%) is close to the sum of the extradural and dumb-bell lesions in adults (11.1%). In children vertebral signs, i.e., spinal rigidity and tenderness, and spasm of paravertebral muscles, are more intense, earlier, and more frequent than in adults, and the clinical history is shorter. The chances of recovery from neurological deficits are greater, as are those of malignant degeneration.
本文回顾了有关儿童脊髓神经鞘瘤（N）和脊膜瘤（M）的文献，并新增了5例个人神经鞘瘤病例（其中1例与冯雷克林霍增氏病有关）。神经鞘瘤病例共计151例，脊膜瘤病例69例，分别占儿童脊髓肿瘤的10.9%和4.3%，占各年龄段脊髓神经鞘瘤和脊膜瘤的2.6%和1.3%。详细分析了61例神经鞘瘤（其中16例与冯雷克林霍增氏病有关）和26例脊膜瘤（其中5例与冯雷克林霍增氏病有关）。神经鞘瘤主要发生在9至15岁之间，男女比例为3:2，脊髓各节段受累情况相同，硬膜外神经鞘瘤或伴有硬膜外成分的情况（48%）比成人（26.9%）更常见。脊膜瘤主要发生在12至15岁之间，男女比例为3:2，胸段的发生率（47.8%）不如成人（81%）明显，硬膜外部位的发生率（10.6%）接近成人硬膜外和哑铃形病变的总和（11.1%）。在儿童中，脊柱体征，即脊柱僵硬、压痛和椎旁肌痉挛，比成人更强烈、出现更早且更频繁，临床病史更短。神经功能缺损恢复的机会更大，恶性变的机会也更大。
