Offori T W, Platt C C, Stephens M, Hopkinson G B
Department of Surgery, North Staffordshire Hospital Centre, Stoke-on-Trent, UK.
Clin Exp Dermatol. 1993 Mar;18(2):174-7. doi: 10.1111/j.1365-2230.1993.tb01008.x.
In cases of congenital lymphoedema the finding of ulceration, violaceous nodules or papules, or apparent traumatic ecchymoses should act as a diagnostic beacon warning of dangers. A case is reported of a high-grade angiosarcoma developing in a patient with congenital hereditary lymphoedema (Milroy's disease). This is the second paper to report this complication, the third case report and the first case in which the diagnosis is substantiated by immunohistochemistry and lectin histochemistry. A review of cases of angiosarcoma complicating congenital hereditary and non-hereditary lymphoedema is also presented.
在先天性淋巴水肿病例中，出现溃疡、紫红色结节或丘疹，或明显的创伤性瘀斑应作为危险的诊断警示信号。本文报告了1例发生于先天性遗传性淋巴水肿（米尔罗伊病）患者的高级别血管肉瘤。这是第二篇报告该并发症的论文，也是第三例病例报告，并且是第一例通过免疫组织化学和凝集素组织化学证实诊断的病例。本文还对并发先天性遗传性和非遗传性淋巴水肿的血管肉瘤病例进行了综述。
