Pace L, Betocchi S, Piscione F, Mangoni di Santo Stefano M L, Chiariello M, Salvatore M
Cattedra di Medicina Nucleare, Istituto di Scienze Radiologiche, Napoli, Italy.
Clin Nucl Med. 1993 Apr;18(4):286-90. doi: 10.1097/00003072-199304000-00004.
Myocardial perfusion and function were evaluated with Tc-99m MIBI myocardial scintigraphy before and after percutaneous angioplasty in six patients. In addition to conventional stress-rest images (3 projections: 45 degrees left anterior oblique, anterior, and left lateral), gated images were obtained at rest and during stress before and after angioplasty. Improvement in myocardial perfusion after angioplasty was demonstrated in all patients. The increase from rest to stress of radionuclide fractional shortening (an index of global left ventricular function computed on gated images) was greater after angioplasty than before (9% +/- 7% versus--0.5% +/- 8%, respectively, p < 0.05). Systolic wall thickening (an index of regional left ventricular function) showed a significantly greater rest-to-stress increase after angioplasty than before it in the regions supplied by treated vessels. Thus, Tc-99m MIBI myocardial scintigraphy is capable of evaluating myocardial perfusion and function.
对6例患者在经皮血管成形术前后用锝-99m甲氧基异丁基异腈心肌闪烁显像评估心肌灌注和功能。除了常规的静息-负荷图像（3个投照位：左前斜45度、前位和左侧位）外，还在血管成形术前后的静息和负荷状态下获取门控图像。所有患者血管成形术后心肌灌注均有改善。血管成形术后放射性核素分数缩短率（根据门控图像计算的左心室整体功能指标）从静息到负荷的增加大于术前（分别为9%±7%和-0.5%±8%，p<0.05）。在治疗血管供血区域，收缩期室壁增厚（左心室局部功能指标）在血管成形术后静息到负荷的增加明显大于术前。因此，锝-99m甲氧基异丁基异腈心肌闪烁显像能够评估心肌灌注和功能。
