Fortin D, Coulon J F, Roberge A G
INRS-Santé, Université du Québec, Pointe-Claire, Canada.
Comp Biochem Physiol B. 1993 Mar;104(3):567-75. doi: 10.1016/0305-0491(93)90283-b.
The specific adrenal dopamine-beta-hydroxylase activity measured in cat and rat was: (1) two times higher in cat than in rat; (2) significantly enhanced by ascorbate (up to 5 mM) that acts as a major activator; (3) differently affected by exogenous copper added to the incubation medium, leading to a decrease with large concentrations; and (4) similar, according to the kinetic parameters, thereby demonstrating a greater affinity for ascorbate than for tyramine.
