细菌诱导红细胞T抗原激活并发坏死性小肠结肠炎：一例报告

Bacterial-induced activation of erythrocyte T-antigen complicating necrotising enterocolitis: a case report.

作者信息

Mupanemunda R H, Kenyon C F, Inwood M J, Leigh K

机构信息

Department of Paediatrics, University of Western Ontario, London, Canada.

出版信息

Eur J Pediatr. 1993 Apr;152(4):325-6. doi: 10.1007/BF01956745.

DOI:10.1007/BF01956745

PMID:8482283

Abstract

Erythrocyte Thomsen-Friedenreich crypt antigen (T-antigen) activation is not an uncommon event in infants with severe necrotising enterocolitis (NEC). Transfusion of these infants with blood products containing plasma carries the risk of causing intravascular haemolysis. T-antigen activation is easily detected using a rapid simple lectin agglutination test. Early recognition of T-antigen activation ensures the correct choice of plasma free transfusion therapy. We describe an infant with severe NEC complicated by T-antigen activation and haemolysis.

摘要

红细胞汤姆森-弗里德赖希隐抗原（T抗原）激活在患有严重坏死性小肠结肠炎（NEC）的婴儿中并非罕见事件。给这些婴儿输注含有血浆的血液制品有导致血管内溶血的风险。使用快速简单的凝集素凝集试验很容易检测到T抗原激活。早期识别T抗原激活可确保正确选择无血浆输血疗法。我们描述了一名患有严重NEC并伴有T抗原激活和溶血的婴儿。