Lestàr B, Penninckx F, Bouckaert W, Geboes K, Kerremans R
Department of Abdominal Surgery, University Clinic Gasthuisberg, Catholic University Leuven, Belgium.
Eur Surg Res. 1993 Mar-Apr;25(2):123-8. doi: 10.1159/000129266.
Three types of colonic sphincter substitutes were placed at an abdominal colostomy in dogs. Simple valve construction (8) was based on orthograde intussusception of the colon over 3.5 cm. In calibrated valves (6) the intraluminal pressure was increased by reducing the diameter of the overlying muscle coat. Reverse smooth muscle plasties (5) and simple colostomies (5) served as controls. Immediately after construction highest pressure (50 +/- 8.9 mm Hg) was obtained in calibrated valves. After 1 month the pressure dropped to 20 mm Hg, but remained stable thereafter. Although valvular constructions cannot maintain high pressure, they may be useful as substitutes for the internal anal sphincter by filling up the lumen so that the action of a surrounding striated muscle ring becomes more effective.
三种类型的结肠括约肌替代物被置于犬的腹部结肠造口处。简单瓣膜构造（8例）基于3.5厘米以上结肠的顺行套叠。在校准瓣膜（6例）中，通过减小覆盖肌层的直径来增加腔内压力。反向平滑肌成形术（5例）和简单结肠造口术（5例）作为对照。构建后立即在校准瓣膜中获得最高压力（50±8.9毫米汞柱）。1个月后压力降至20毫米汞柱，但此后保持稳定。虽然瓣膜构造不能维持高压，但它们通过填充管腔可能作为肛门内括约肌的替代物有用，从而使周围横纹肌环的作用更有效。
