Kapur S P
Acta Anat (Basel). 1977;97(2):200-4. doi: 10.1159/000144734.
A fine-structure study of the parathyroid proper and adjacent tissues has been performed in the gerbils. The chief cells were observed in three phases of the secretory cycle. The resting chief cells contained prominent lipid droplets, mitochondria and an atrophied Golgi apparatus in a finely granular cytoplasm. The intermediate-phase chief cells were also rich in lipid but showed an organelle assembly which is much less developed than in the actively secreting cells. The active chief cells possessed a noncisternal rough endoplasmic reticulum, located often in close proximity of the mitochondria. A prominent Golgi apparatus, numerous pro-secretory granules and lysosomes are characteristic of the active cells. The significance of these morphological variations is discussed. Large mitochondria-rich cells, akin to oxyphil cells were observed in the tissue adjacent to the parathyroid proper.
在沙鼠身上对甲状旁腺本体及相邻组织进行了超微结构研究。观察到主细胞处于分泌周期的三个阶段。静止期主细胞在细颗粒状细胞质中含有显著的脂滴、线粒体和萎缩的高尔基体。中间期主细胞也富含脂质，但细胞器组装比活跃分泌细胞中的要少得多。活跃期主细胞拥有非池状粗面内质网，常位于线粒体附近。活跃细胞的特征是有突出的高尔基体、大量前分泌颗粒和溶酶体。讨论了这些形态学变化的意义。在甲状旁腺本体相邻的组织中观察到类似于嗜酸性细胞的富含线粒体的大细胞。
