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长爪沙鼠(Meriones unguiculatus)甲状腺滤泡旁(C)细胞的组织化学和超微结构研究。

Histochemical and ultrastructural study of the parafollicular (C) cells in the thyroid of the gerbil, Meriones unguiculatus.

作者信息

Kapur S P

出版信息

Acta Anat (Basel). 1977;99(1):43-53. doi: 10.1159/000144833.

DOI:10.1159/000144833
PMID:899684
Abstract

A histochemical and electron-microscopic study has been done on the parafollicular (C) cells of the thyroid in the gerbil. Histochemical tests revealed the characteristic presence of alpha-glycerophosphoric dehydrogenase and the presence of phenolic groups and indoleamines. Acid phosphatase levels were similar to those observed in the apical cytoplasm of the follicular cells. Electron microscopy revealed characteristic presence of noncisternal rough endoplasmic reticulum, well-developed Golgi apparatus, numerous prosecretory granules and a few electrondense mature secretory granules. Most characteristic of these cells was the presence of numerous, large, electron-lucent vesicles which often were packed in the cytoplasmic processes that were located subjacent to the follicular cells and close to the blood capillaries. Significance of these histochemical and ultrastructural findings is emphasized particularly in regard to the presence of monoamines and their possible role in the release of calcitonin and thyroxin.

摘要

对沙鼠甲状腺滤泡旁(C)细胞进行了组织化学和电子显微镜研究。组织化学测试显示存在α-甘油磷酸脱氢酶以及酚基团和吲哚胺。酸性磷酸酶水平与在滤泡细胞顶端细胞质中观察到的水平相似。电子显微镜显示存在非池状粗面内质网、发达的高尔基体、大量前分泌颗粒和一些电子致密的成熟分泌颗粒。这些细胞最典型的特征是存在大量大的电子透明囊泡,这些囊泡常常聚集在位于滤泡细胞下方并靠近毛细血管的细胞质突起中。特别强调了这些组织化学和超微结构发现的意义,尤其是关于单胺的存在及其在降钙素和甲状腺素释放中可能发挥的作用。

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Acta Anat (Basel). 1977;99(1):43-53. doi: 10.1159/000144833.
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