Cohen R A, Kessler H R, Fischer M
Department of Neurology, University of Massachusetts Medical Center, Worcester 01655.
J Neurol Sci. 1993 Apr;115(2):132-5. doi: 10.1016/0022-510x(93)90215-k.
We investigated the relationship between the Kurtzke expanded disability status scale (EDSS) and an activities of daily living (ADL) scale that assesses disability across multiple functional domains based on self report of patients with multiple sclerosis (MS). Forty-three patients with definite MS responded on a 42-item ADL inventory and were also assigned an EDSS rating as part of their regular clinical examination. While a strong correlation was found between the EDSS and total ADL disability level, the ADL domain of 'Mobility' fully accounted for this relationship. The distribution of ADL scores as a function of EDSS level was curvilinear, as ADL variance was inconsistent across EDSS levels. Little ADL disability was evident when EDSS levels were below five. At higher EDSS levels, ADL variability increased substantially, making predictions regarding ADL level less exact.
我们研究了库尔茨克扩展残疾状态量表（EDSS）与日常生活活动（ADL）量表之间的关系，该ADL量表基于多发性硬化症（MS）患者的自我报告，评估多个功能领域的残疾情况。43例确诊为MS的患者对一份包含42个条目的ADL问卷进行了回答，并且在其常规临床检查中还被评定了EDSS等级。虽然在EDSS与ADL总残疾水平之间发现了很强的相关性，但“移动性”这一ADL领域完全解释了这种关系。ADL分数作为EDSS水平的函数分布呈曲线状，因为ADL方差在不同的EDSS水平上并不一致。当EDSS水平低于5时，几乎没有明显的ADL残疾。在较高的EDSS水平上，ADL变异性大幅增加，使得对ADL水平的预测变得不那么准确。
