Wöckel W, Eckert J, Löscher T, Häussinger K, Morresi A
Pathologisches Institut, Zentralkrankenhauses Gauting der LVA Oberbayern.
Pneumologie. 1993 Mar;47(3):227-31.
Two intrapulmonary round nodules were identified by x-ray examination in a 45-year old German woman during an examination conducted before her employment who had been complaining of pain in the right side of the thorax and of mild coughing irritation and tiredness for several months prior to the health check. Since the intraoperative frozen section did not show any malignancy, and atypical resection of the two involved segments was performed. Histological processing of the surgical specimens showed two spherical ischemic necroses surrounded by a connective tissue border with inflammatory infiltration. In the centre of the larger of the two necrotic lesions a parasite was seen intravascularly, which because of morphological and serological findings, was identified as a Dirofilaria. It must be assumed that the infection of this patient occurred during a stay in Corsica where these nematodes are endemic in several mammal hosts. The patient was therefore suffering from an autochthonous European dirofilariasis of the lung. Only two cases of this infection acquired in Europe have been reported so far.
在一名45岁德国女性入职前的体检中，X光检查发现其双肺有两个圆形结节。该女性在健康检查前几个月一直抱怨右胸疼痛、有轻度咳嗽刺激感和疲劳。由于术中冰冻切片未显示任何恶性迹象，遂对两个受累节段进行了非典型切除。手术标本的组织学检查显示有两个球形缺血性坏死灶，周围有结缔组织边界伴炎症浸润。在两个坏死病变中较大的一个中心，血管内可见一条寄生虫，根据形态学和血清学检查结果，确定为犬恶丝虫。必须假定该患者是在科西嘉岛逗留期间感染的，那里这些线虫在几种哺乳动物宿主中呈地方性流行。因此，该患者患有肺内源性欧洲恶丝虫病。迄今为止，欧洲仅报告了两例这种感染病例。
