Gelardi R C, Mountford M K
Infant Formula Council, Atlanta, Georgia 30342.
Regul Toxicol Pharmacol. 1993 Apr;17(2 Pt 1):181-92. doi: 10.1006/rtph.1993.1016.
Concern about the effect of potential pesticide residues on the safety of the U.S. food supply has led to extensive modeling and projections of worst-case scenarios. Many risk assessment models project risk based on an assumption of the presence of pesticide residues at the tolerance level or at a level equivalent to the limit of analytical detectability. Often, actual residue data, and the variability of analytical detection limits, are ignored in favor of simpler models. Data presented here demonstrate the absence of detectable levels of pesticides in infant formula. The range of detection limits of analytical methodology employed also are presented. A rationale for the absence of pesticide residues in infant formulas derived from plant and animal sources is presented which obviates worst-case scenario calculations of risk based on pesticide residue tolerance levels or method detection limits.
对潜在农药残留对美国食品供应安全的影响的担忧导致了对最坏情况的广泛建模和预测。许多风险评估模型基于农药残留处于耐受水平或等同于分析可检测限水平的假设来预测风险。通常,实际残留数据以及分析检测限的变异性被忽视,而倾向于更简单的模型。此处呈现的数据表明婴儿配方奶粉中不存在可检测到的农药水平。还列出了所采用分析方法的检测限范围。提出了植物和动物来源的婴儿配方奶粉中不存在农药残留的理由,这使得基于农药残留耐受水平或方法检测限的最坏情况风险计算变得不必要。