Luttkus A, Windel K, Dudenhausen J W
Arbeitsgruppe für Perinatale Medizin, Freien Universität Berlin.
Z Geburtshilfe Perinatol. 1993 Jan-Feb;197(1):31-7.
In an open prospective investigation the median levels of C-reactive protein were determined in annormal collective. The median lies at 0.8 mg/dl in maternal serum withdrawn sub partu and in umbilical vein blood, and at 1.45 mg/dl immediately after ligation of the cord. Hopes on finding a biochemical parameter that could supply reliable information already during labour on a possible inflammatory infection in mother and child, did not materialize from the data found. Prediction of an infection of the newborn using CPR is only minimal. The most important practical information is given by the negative CRP in the umbilical vein blood. In this case the probability of an infection of the newborn is very slight. A high temperature during labour was the best predictor of the probability of endometritis puerperalis. This clinical finding, due to its specificity, is superior to CRP and the other parameters investigated.
在一项开放性前瞻性研究中，测定了正常人群中C反应蛋白的中位数水平。产后抽取的母血血清和脐静脉血中C反应蛋白的中位数为0.8mg/dl，脐带结扎后立即测定的值为1.45mg/dl。希望找到一种生化参数，能够在分娩期间就为母婴可能发生的炎症感染提供可靠信息，但从所获数据来看并未实现。使用C反应蛋白预测新生儿感染的可能性极低。最重要的实际信息是脐静脉血中C反应蛋白呈阴性。在这种情况下，新生儿感染的可能性非常小。分娩期间体温升高是产褥期子宫内膜炎发生概率的最佳预测指标。这一临床发现因其特异性，优于C反应蛋白及其他所研究的参数。
