Gado K, Emery P
Department of Rheumatology, Selly Oak and Queen Elizabeth Hospital, Birmingham, United Kingdom.
Ann Rheum Dis. 1993 Mar;52(3):215-8. doi: 10.1136/ard.52.3.215.
Chronic shoulder pain is a common and disabling symptom in patients with rheumatoid arthritis (RA). It has been previously shown that a suprascapular nerve block (SSNB) using the standard mixture of bupivacaine and adrenaline (Ba) plus methylprednisolone (P), which is routinely used in pain clinics, results in a considerable improvement in pain relief and range of movement compared with conventional intra-articular steroid injections in such patients. A double blind study was carried out in 29 patients (58 shoulders) with RA to compare SSNB induced with Ba alone with that induced using the conventional mixture of Ba plus P. Highly significant improvements were noted in measures of pain, stiffness, and range of most movements for both treatments (up to three months) compared with baseline. Results favoured Ba alone; the differences between the two treatments reached statistical significance for stiffness (at 12 weeks) and active abduction (at one week). It is concluded that the addition of P to the SSNB mixture confers no benefit in these patients.
慢性肩部疼痛是类风湿性关节炎(RA)患者常见的致残症状。先前研究表明,在疼痛诊所常规使用的布比卡因与肾上腺素(Ba)加甲基强的松龙(P)的标准混合物进行肩胛上神经阻滞(SSNB),与传统关节内注射类固醇相比,能显著改善此类患者的疼痛缓解情况和活动范围。对29例(58个肩部)RA患者进行了一项双盲研究,比较单独使用Ba诱导的SSNB与使用Ba加P的传统混合物诱导的SSNB。与基线相比,两种治疗方法(长达三个月)在疼痛、僵硬和大多数运动范围的测量方面均有高度显著改善。结果支持单独使用Ba;两种治疗方法在僵硬(12周时)和主动外展(1周时)方面的差异具有统计学意义。结论是,在SSNB混合物中添加P对这些患者没有益处。