Hofer M A, Shair H N
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York.
Behav Neurosci. 1993 Apr;107(2):354-62. doi: 10.1037//0735-7044.107.2.354.
In these experiments we tested the hypothesis that the respiratory events underlying rat pup ultrasonic vocalization (USV) facilitate brown adipose tissue (BAT) thermogenesis, as proposed by Blumberg and Alberts (1990). Laryngeal denervation or tracheostomy were used to reduce or eliminate laryngeal braking and prevent USV in 9- to 10-day-old pups during recovery from deep hypothermia and during cooling induced by isolation for 1 hr at room temperature. Both forms of devocalization slowed rewarming of hypothermic pups, but neither had any effects on cooling rate or BAT thermogenesis in normothermic pups that were allowed to cool from 35 degrees C to 29 degrees C. Physiological effects of laryngeal braking on thermogenesis appear to be limited to conditions, such as severe hypothermia, in which ventilatory and oxygen transport functions are compromised. The results have implications for understanding the regulation and evolution of USV.
在这些实验中，我们检验了一个假设，即如布伦伯格和艾伯茨（1990年）所提出的，大鼠幼崽超声波发声（USV）背后的呼吸事件促进棕色脂肪组织（BAT）产热。在9至10日龄幼崽从深度低温恢复期间以及在室温下隔离诱导冷却1小时的过程中，使用喉去神经支配或气管切开术来减少或消除喉部制动并防止USV。两种形式的发声抑制都减缓了低温幼崽的复温速度，但对从35摄氏度冷却至29摄氏度的正常体温幼崽的冷却速率或BAT产热均无任何影响。喉部制动对产热的生理影响似乎仅限于诸如严重低温等通气和氧气运输功能受损的情况。这些结果对于理解USV的调节和进化具有启示意义。
