费拉拉省的群体遗传学。二、库利贫血患儿的生存情况。
Population genetics in the province of Ferrara. II. Survival of children with Cooley's anemia.
作者信息
Cucchi P, Vullo C, Barrai I
出版信息
Am J Hum Genet. 1977 Mar;29(2):178-83.
The demographic data of children with Cooley's anemia seen at the thalassemia center in Ferrara were analyzed. Survival was studied as a function of several variables, the most interesting being the distance between birthplaces of the parents of affected children. This distance was considered an indicator of genetic distance, and therefore an indicator of residual hybridity of the children. The significant regression of survival on interparental distance might be interpreted as an indicator of increased survival due to residual hybridity. The significant correlation of survival with expected hybridity supports this interpretation.
对在费拉拉地中海贫血中心就诊的库利贫血患儿的人口统计学数据进行了分析。将生存率作为几个变量的函数进行研究，其中最有趣的是患病儿童父母出生地之间的距离。这个距离被视为遗传距离的指标，因此也是儿童残余杂种性的指标。生存率与父母间距离的显著回归可能被解释为由于残余杂种性导致生存率提高的一个指标。生存率与预期杂种性的显著相关性支持了这一解释。
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