费拉拉省的群体遗传学。I. 遗传距离与地理距离。

Population genetics in the province of Ferrara. I. Genetic distances and geographic distances.

作者信息

Zanardi P, Dell'Acqua G, Menini C, Barrai I

出版信息

Am J Hum Genet. 1977 Mar;29(2):169-77.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1685266/

Abstract

The ABO and Rh systems of the population in 26 residential units in the province of Ferrara were studied to detect the effect of genetic drift on the differentiation of gene frequencies. Results obtained from principal components analysis and dendrograms were similar. A significant correlation between genetic and geographic distance was found. It was therefore hypothesized that in the area of Ferrara children born to parents originating from different communes were heterozygous at more loci than children born to parents originating from the same commune. It was also thought that it may be possible to use geographic distance between birthplaces of parents as an indicator of hybridity in their children.

摘要

对费拉拉省26个居住单元人群的ABO和Rh血型系统进行了研究，以检测基因漂变对基因频率分化的影响。主成分分析和树状图得到的结果相似。发现基因距离与地理距离之间存在显著相关性。因此，有人推测，在费拉拉地区，父母来自不同公社的孩子比父母来自同一公社的孩子在更多基因座上是杂合的。还认为有可能将父母出生地之间的地理距离作为其子女杂合性的一个指标。

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