García-Arenzana J M, Alcorta M, Díaz de Tuesta J L, Idígoras P, Pérez-Trallero E
Servicio de Microbiología, Hospital Ntra. Sra. de Aránzazu, San Sebastián.
An Med Interna. 1993 Mar;10(3):116-8.
The anti-pneumococcal vaccine, with 23 capsular polysaccharides, is an effective vaccine used in most of the developed countries, although still not commercially available in Spain. Between January 1981 and June 1992, we isolated 784 Streptococcus pneumoniae from clinical samples (excluding asymptomatic carriers), 728 of which could be serotyped (300 isolated in hemoculture and/or LCR). 91.5% of the total and 93.3% of the most invasive strains, as well as 98.1% of the penicillin-resistant strains or 98.8% of the isolated multiresistant strains, presented a serotype covered by the current vaccine. The high resistance to antibiotics of the pneumococcus in Spain makes more urgent the indication of the vaccine in our community.
含有23种荚膜多糖的抗肺炎球菌疫苗是一种在大多数发达国家使用的有效疫苗，尽管在西班牙仍未上市。1981年1月至1992年6月期间，我们从临床样本（不包括无症状携带者）中分离出784株肺炎链球菌，其中728株可进行血清分型（300株在血液培养和/或LCR中分离）。在全部菌株中，91.5%、侵袭性最强的菌株中93.3%、青霉素耐药菌株中98.1%或分离出的多重耐药菌株中98.8%，呈现出当前疫苗所涵盖的血清型。西班牙肺炎球菌对抗生素的高耐药性使得在我们社区更迫切需要接种该疫苗。
