Kaiser-Kupfer M, Kuwabara T, Kupfer C
Am J Ophthalmol. 1977 Mar;83(3):340-6. doi: 10.1016/0002-9394(77)90730-9.
Bilateral progressive essential iris atrophy, more advanced in one eye than in the other, occurred in a 24-year-old white man. Histopathologic examination of the iris from the eye with the more advanced iris atrophy disclosed no vascular abnormalities in that the vessels were patent and appeared normal except for accumulated perivascular connective tissue. Fluorescein angiographic examination of the fellow eye that was undergoing the earliest changes of iris atrophy failed to reveal any vascular abnormalities. However, tonographic examination indicated a markedly decreased outflow facility. There does not appear to be any vascular abnormality involved in the pathogenesis.
一名24岁白人男性出现双侧进行性原发性虹膜萎缩，一只眼睛比另一只眼睛病情更严重。对虹膜萎缩更严重那只眼睛的虹膜进行组织病理学检查，未发现血管异常，因为血管通畅，除了血管周围结缔组织积聚外，看起来正常。对正在发生虹膜萎缩早期变化的另一只眼睛进行荧光素血管造影检查，未发现任何血管异常。然而，眼压描记检查显示房水流畅系数明显降低。发病机制中似乎不存在任何血管异常。
