Kupfer C, Kaiser-Kupfer M, Kuwabara T
Trans Am Ophthalmol Soc. 1976;74:341-56.
A case of bilateral progressive essential iris atrophy, more advanced in one eye than the other, has been studied. Histopathologic examination of the iris from the eye with the more advanced iris atrophy failed to find any vascular abnormalities in that the vessels were patent and appeared normal except for accumulated perivascular connective tissue. Fluorescein angiographic examination of the right eye which was undergoing the earliest changes of iris atrophy failed to show any vascular abnormalities. However, tonographic examination indicated a markedly decreased outflow facility. There does not appear to be any vascular abnormality involved in the pathogenesis of this case.
已对一例双眼进行性原发性虹膜萎缩病例进行了研究，其中一只眼睛的病情比另一只眼睛更严重。对虹膜萎缩更严重的那只眼睛的虹膜进行组织病理学检查，未发现任何血管异常，因为血管通畅，除了血管周围结缔组织积聚外，外观正常。对最早出现虹膜萎缩变化的右眼进行荧光素血管造影检查，未显示任何血管异常。然而，眼压描记检查表明房水流畅系数明显降低。该病例的发病机制似乎不存在任何血管异常。
