deBoisblanc B P, Castro M, Everret B, Grender J, Walker C D, Summer W R
Department of Medicine, Louisiana State University Medical School, New Orleans.
Chest. 1993 May;103(5):1543-7. doi: 10.1378/chest.103.5.1543.
We hypothesized that continuous, automatic turning utilizing a patient-friendly, low air loss surface would reduce the incidence of early ICU pneumonia in selected groups of critically ill medical patients.
Prospective, randomized, controlled clinical trial.
Medical ICU of a large community teaching hospital.
One hundred twenty-four critically ill new admissions to the medical ICU at Charity Hospital in New Orleans.
Patients were prospectively randomized within one of five diagnosis-related groups (DRG)--sepsis (SEPSIS), obstructive airways disease (OAD), metabolic coma, drug overdose, and stroke--to either routine turning on a standard ICU bed or to continuous turning on an oscillating air-flotation bed for a total of five days.
Patients were monitored daily during the treatment period for the development of pneumonia. The incidence of pneumonia during the first five ICU days was 22 percent in patients randomized to the standard ICU bed vs 9 percent for the oscillating bed (p = 0.05). This treatment effect was greatest in the SEPSIS DRG (23 percent vs 3 percent, p = 0.04). Continuous automatic oscillation did not significantly change the number of days of required mechanical ventilation, ICU stay, hospital stay, or hospital mortality overall or within any of the DRGs.
We conclude that air-supported automated turning during the first five ICU days reduces the incidence of early ICU pneumonia in selected DRGs; however, this form of automated turning does not reduce other measured clinical outcome parameters.
我们假设,使用患者友好型低气损表面进行持续自动翻身,可降低特定重症内科患者群体早期ICU肺炎的发生率。
前瞻性、随机、对照临床试验。
一家大型社区教学医院的内科重症监护病房。
新奥尔良慈善医院内科重症监护病房的124例新入院重症患者。
患者在五个诊断相关组(DRG)之一(脓毒症(SEPSIS)、阻塞性气道疾病(OAD)、代谢性昏迷、药物过量和中风)内被前瞻性随机分组,分别在标准ICU床上进行常规翻身,或在振荡气浮床上进行持续翻身,共五天。
在治疗期间,每天监测患者是否发生肺炎。随机分配到标准ICU床的患者在入住ICU的前五天内肺炎发生率为22%,而振荡床组为9%(p = 0.05)。这种治疗效果在脓毒症DRG组中最为显著(23% 对 3%,p = 0.04)。持续自动振荡并未显著改变所需机械通气天数、ICU住院时间、住院时间或总体及任何DRG组内的医院死亡率。
我们得出结论,在入住ICU的前五天内进行气浮支持的自动翻身可降低特定DRG组中早期ICU肺炎的发生率;然而,这种自动翻身形式并未降低其他所测量的临床结局参数。