Ashtekar M D, Samuel A M, Kadival G V, Sakhalkar V, Rajadhyaksha S, Virdi S S
Radiation Medicine Centre, Bhabha Atomic Research Centre, Bombay.
Indian J Med Res. 1993 Jan;97:14-7.
T cells and their sub-populations were evaluated with respect to reactive, intermediate and unreactive forms of tuberculosis as classified by Lenzini. Significant CD4 lymphopenia and a reduction of CD4/CD8 ratios were found in patients with reactive tuberculosis. It was observed that there was a B lymphocytosis, CD8 lymphocytosis and a reduction of CD4/CD8 ratio in patients with intermediate and unreactive forms of tuberculosis. The T lymphocytes and CD4 subset were unchanged. There was no significant difference in the lymphocytes and sub-populations among the intermediate and unreactive groups.
根据伦齐尼的分类，对T细胞及其亚群在反应性、中间型和无反应性肺结核中的情况进行了评估。在反应性肺结核患者中发现了显著的CD4淋巴细胞减少以及CD4/CD8比值降低。观察到在中间型和无反应性肺结核患者中存在B淋巴细胞增多、CD8淋巴细胞增多以及CD4/CD8比值降低的情况。T淋巴细胞和CD4亚群没有变化。中间型和无反应性组之间的淋巴细胞及其亚群没有显著差异。
