Husu J, Syväoja E L, Ahola-Luttila H, Kalsta H, Sivelä S, Kosunen T U
Department of Bacteriology and Serology, National Veterinary Institute, Helsinki, Finland.
J Appl Bacteriol. 1993 May;74(5):564-9.
Serial immunization of dairy cows with Campylobacter jejuni resulted in an enhanced serum antibody response and production of hyperimmune colostrum in all vaccinated animals. An approximate 10-fold decrease in the Camp. jejuni-specific antibody titres in colostrum was observed within 2 d post-partum. The lyophilized colostral concentrate fed to newborn calves resulted in a rapid increase in serum antibody response. Specific Camp. jejuni immunoglobulins could be detected in these animals for a further 10 weeks. The lyophilized hyperimmunized colostrum was very stable in vitro at different storage temperatures. It could be used for passive immunization to campylobacteriosis.
