21号染色体位点与家族性肌萎缩侧索硬化症之间不存在连锁关系。
Absence of linkage between chromosome 21 loci and familial amyotrophic lateral sclerosis.
作者信息
King A, Houlden H, Hardy J, Lane R, Chancellor A, de Belleroche J
机构信息
Department of Biochemistry, Charing Cross and Westminister Medical School, London.
出版信息
J Med Genet. 1993 Apr;30(4):318. doi: 10.1136/jmg.30.4.318.
Abstract
Familial amyotrophic lateral sclerosis (FALS) has recently been shown to be linked to chromosome 21 markers in a subset of families. However, we were unable to show linkage between FALS and chromosome 21 markers which flank the putative FALS locus in UK families.
摘要
家族性肌萎缩侧索硬化症（FALS）最近已被证明在一部分家族中与21号染色体标记物有关。然而，我们无法在英国家族中显示FALS与位于假定FALS基因座两侧的21号染色体标记物之间存在连锁关系。
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