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开胸或不开胸的食管切除术。有什么区别吗?

Esophagectomy with or without thoracotomy. Is there any difference?

作者信息

Tilanus H W, Hop W C, Langenhorst B L, van Lanschot J J

机构信息

Department of Surgery, Erasmus University Hospital, Rotterdam, The Netherlands.

出版信息

J Thorac Cardiovasc Surg. 1993 May;105(5):898-903.

PMID:8487568
Abstract

Two operative approaches for esophageal carcinoma were compared with respect to operative morbidity and mortality by means of multivariable analysis. From 1980 to 1986, 152 patients underwent resection by laparotomy and right-sided anterolateral thoracotomy with an intrathoracic anastomosis. From 1986 to 1989, 141 patients underwent resection by transhiatal blunt dissection with a cervical anastomosis. The stomach was the preferred organ for reconstruction. Paresis of the recurrent laryngeal nerve and leakage of the cervical anastomosis occurred significantly more often in the transhiatal group. Pulmonary complications occurred less frequently in the transhiatal group. In-hospital mortality (9% in the thoracotomy group and 5% in the transhiatal group) increased significantly with advanced age of the patients. Furthermore, it was significantly higher in case of colonic interposition as compared with reconstruction with the stomach. Long-term survival did not differ between the two groups. Especially for carcinomas in the distal part of the esophagus, transhiatal esophageal resection without thoracotomy seems to be an oncologically justifiable operation with a reduced morbidity and mortality.

摘要

通过多变量分析比较了两种食管癌手术方法的手术发病率和死亡率。1980年至1986年,152例患者接受了经剖腹术和右侧前外侧开胸术并进行胸内吻合的切除术。1986年至1989年,141例患者接受了经裂孔钝性分离并进行颈部吻合的切除术。胃是重建的首选器官。喉返神经麻痹和颈部吻合口漏在经裂孔组中明显更常见。经裂孔组肺部并发症发生频率较低。患者年龄越大,住院死亡率(开胸组为9%,经裂孔组为5%)显著升高。此外,与用胃重建相比,结肠代食管时住院死亡率显著更高。两组的长期生存率无差异。特别是对于食管远端的癌,不经开胸的经裂孔食管切除术似乎是一种在肿瘤学上合理的手术,其发病率和死亡率较低。

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