Roder D, Chan A, Esterman A
Epidemiology Branch, South Australian Health Commission, Adelaide.
Med J Aust. 1993 May 17;158(10):664-7. doi: 10.5694/j.1326-5377.1993.tb121911.x.
To investigate differences by birthweight in risk of perinatal death between level 3 hospitals (which provide care for high risk pregnancies and neonatal intensive care) and other hospitals in South Australia, using perinatal data for the 1985-1990 period.
Analysis of birthweight-specific trends in risk of perinatal death by hospital category for singleton births, adjusting for risk factors.
114 725 singleton births of at least 400 g birthweight (or at least 20 weeks' gestation) born in hospitals in the 1985-1990 period and notified to the perinatal data collection.
The relative odds of a perinatal death, as opposed to a live birth which survived the neonatal period.
Births at level 3 hospitals had a higher crude risk of perinatal death than those at other hospitals, but this was due to the higher frequency of low birthweights at level 3 hospitals. For birthweights under 2000 g, and especially for the very low birth-weights, there was a higher risk at non-level-3 than level 3 hospitals. There was also the unexpected finding that births at level 3 hospitals in the 2500-2999 g range had a comparatively high risk of perinatal death. There was little difference in risk for births of higher birthweight.
The greatly reduced risk of perinatal death in level 3 hospitals for babies with birthweights under 2000 g seems likely to be due to the specialist services in these hospitals. Further investigation is required to determine why babies in the 2500-2999 g range of birthweights had a comparatively high risk of perinatal death at these hospitals. This appears to be due, at least in part, to an excess contribution of deaths from congenital abnormalities. Also, it seems that the higher prevalence of complications in pregnancy in level 3 hospitals, and the transfers for induction of labour after intrauterine fetal death, would have made a contribution. These same factors may also have affected the risk in level 3 hospitals for higher birthweight births.
利用1985 - 1990年期间的围产期数据,调查南澳大利亚州三级医院(提供高危妊娠护理和新生儿重症监护)与其他医院之间,按出生体重划分的围产期死亡风险差异。
分析单胎分娩按医院类别划分的围产期死亡风险的出生体重特异性趋势,并对风险因素进行调整。
1985 - 1990年期间在医院出生、出生体重至少400克(或妊娠至少20周)且被纳入围产期数据收集的114725例单胎分娩。
围产期死亡相对于新生儿期存活活产的相对比值。
三级医院分娩的围产期死亡粗风险高于其他医院,但这是由于三级医院低出生体重的频率较高。对于出生体重低于2000克的情况,尤其是极低出生体重,非三级医院的风险高于三级医院。还有一个意外发现,出生体重在2500 - 2999克之间的三级医院分娩有相对较高的围产期死亡风险。出生体重较高的分娩风险差异不大。
三级医院中出生体重低于2000克的婴儿围产期死亡风险大幅降低似乎是由于这些医院的专科服务。需要进一步调查以确定为什么出生体重在2500 - 2999克之间的婴儿在这些医院有相对较高的围产期死亡风险。这似乎至少部分是由于先天性异常导致的死亡贡献过多。此外,三级医院妊娠并发症患病率较高以及宫内胎儿死亡后引产的转诊可能也有影响。这些相同因素可能也影响了三级医院中出生体重较高的分娩风险。