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纳洛酮对针刺退热作用的影响。

Effect of naloxone on the antipyretic action of acupuncture.

作者信息

Nezhentsev M, Aleksandrov S

机构信息

Department of Pharmacology, Paediatric Medical Institute, St. Petersburg, Russia.

出版信息

Pharmacology. 1993 May;46(5):289-93. doi: 10.1159/000139057.

DOI:10.1159/000139057
PMID:8488173
Abstract

The effect of the opioid antagonist naloxone on the antipyretic action of acupuncture was studied in rabbits. Naloxone (0.1-0.2 mg/kg) when administered intravenously prior to acupuncture reduced the intensity and duration of the antipyretic action of acupuncture only in the initial stage. The data suggest participation of an endogenous opioid system in initiation of a number of responses mediating the antipyretic effect of acupuncture.

摘要

在兔子身上研究了阿片类拮抗剂纳洛酮对针刺退热作用的影响。在针刺前静脉注射纳洛酮(0.1 - 0.2毫克/千克),仅在初始阶段降低了针刺退热作用的强度和持续时间。数据表明内源性阿片系统参与了介导针刺退热效应的多种反应的启动。

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