Reed M W, O'Leary D P, Duncan J L, Majeed A W, Wright B, Reilly C S
University Dept. of Surgery, University of Sheffield, U.K.
Scand J Gastroenterol. 1993 Apr;28(4):319-22. doi: 10.3109/00365529309090249.
The effects of supplemental oxygen therapy on arterial oxygen saturation (SaO2) in unsedated and sedated patients have been studied using pulse oximetry. Hypoxia (minimum SaO2 92% or less) occurred in 41% of unsedated patients breathing room air but in only 11% (p < 0.01) of those receiving supplemental oxygen (41/min) by nasal cannulae. Comparable effects were seen in sedated patients (60% versus 16%, respectively, p < 0.01). Hypoxia during upper alimentary tract endoscopy is common with or without sedation and can be reduced by supplemental oxygen.
已使用脉搏血氧饱和度测定法研究了补充氧气疗法对未镇静和已镇静患者动脉血氧饱和度(SaO2)的影响。在呼吸室内空气的未镇静患者中,41%出现低氧血症(最低SaO2为92%或更低),但通过鼻导管接受补充氧气(4L/分钟)的患者中只有11%出现低氧血症(p<0.01)。在已镇静患者中也观察到类似的效果(分别为60%和16%,p<0.01)。上消化道内镜检查期间,无论是否使用镇静剂,低氧血症都很常见,补充氧气可降低低氧血症的发生率。