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皮肤恶性黑色素瘤的临床表现与治疗

Clinical appearance and treatment of malignant melanoma of the skin.

作者信息

Pakkanen M

出版信息

Ann Chir Gynaecol. 1977;66(1):21-30.

PMID:848848
Abstract

A report is presented on cases of malignant melanoma of the skin recorded in the Finnish Cancer Registry between 1963 and 1968. The material consisted of 693 cases where the diagnosis of melanoma was confirmed by reclassification of the histological specimens and/or by careful perusal of the hospital records. In females melanoma was most frequent on the lower extremities (43%). One half of the tumours of males were located on the trunk and two thirds of these where on the posterior side of the trunk. Most of the tumours were in stage I at the time of diagnosis (males 75%, females 80%). The mean duration of symptoms, was 4.0 months in males and 4.2 months in females. In stage I, the duration of symptoms was under four months in 40% of cases and in stage II in 37% of cases, whereas in stage III this figure was 68%. The most common symptoms were increase in size (46%) and bleeding from the tumour (11%). Only 28 patients were treated radically while "wide" excision was the most common surgical method (48%).

摘要

本文报告了芬兰癌症登记处1963年至1968年期间记录的皮肤恶性黑色素瘤病例。该资料包括693例病例,其中黑色素瘤的诊断通过组织学标本重新分类和/或仔细查阅医院记录得以证实。女性黑色素瘤最常见于下肢(43%)。男性肿瘤的一半位于躯干,其中三分之二位于躯干后侧。大多数肿瘤在诊断时处于I期(男性75%,女性80%)。男性症状的平均持续时间为4.0个月,女性为4.2个月。在I期,40%的病例症状持续时间不到四个月,II期为37%,而III期这一数字为68%。最常见的症状是肿瘤增大(46%)和肿瘤出血(11%)。只有28例患者接受了根治性治疗,而“广泛”切除是最常见的手术方法(48%)。

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