[先天性无胸腺裸鼠的抗弓形虫免疫]
[Antitoxoplasmic immunity on congenitally athymic nude mice].
作者信息
Stadtsbaeder S
出版信息
Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):149-50.
PMID:848869
Abstract
Susceptibility to toxoplasmic infection was found to be the same in Nude mice (nu/nu) as in controls. Vaccination with avirlent toxoplasma (Beverley strains) confered an incomplete immunity to Nude mice: in 20 to 40% of cases, mortality was delayed as compared to unvaccinated control. Cellular (activation of macrophages) and humoral (circulating antibodies) immune responses were partially present in Nude mice.
摘要
研究发现，裸鼠（nu/nu）对弓形虫感染的易感性与对照组相同。用无毒力的弓形虫（贝弗利株）进行疫苗接种，给予裸鼠的免疫力并不完全：在20%至40%的病例中，与未接种疫苗的对照组相比，死亡时间有所延迟。裸鼠体内部分存在细胞免疫反应（巨噬细胞激活）和体液免疫反应（循环抗体）。
Zotero 插件