[Evolution of the immune response against Micrococcus lysodeikticus].

The immune response of rabbits immunized with Micrococcus lysodeikticus freeze-dried bacteria was studied by following the variation of the affinity and the heterogeneity of the antibodies during immunization. Partial or complete amino acid sequences were determined on the isolated light and heavy chains, and comparative studies were initiated in litter mates. No relationship between the affinity and the restriction in heterogeneity was observed. Sequences are indistinguishable from those reported for antibodies of other specificities.