White W L, Sherertz E F, Berg D, Clark R E
Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103.
Arch Pathol Lab Med. 1993 May;117(5):535-9.
Lupus erythematosus (LE) panniculitis, also called lupus profundus, is an uncommon but well-established manifestation of both chronic cutaneous (discoid) LE and systemic LE. Although LE panniculitis characteristically may involve the face, specific parotid and periparotid involvement has not, to the best of our knowledge, been previously reported. We describe the clinicopathologic correlation of two cases of LE panniculitis that presented as apparent primary parotid parenchymal disease; one as a neoplasm, the other as parotiditis. Failure to recognize LE panniculitis resulted in prolonged periods of inappropriate therapy and significant morbidity, including an unnecessary parotidectomy. Lupus erythematosus panniculitis has well-established histologic criteria that should be considered in the differential diagnosis of an unexplained parotid mass.
红斑狼疮（LE）脂膜炎，也称为深部红斑狼疮，是慢性皮肤型（盘状）LE和系统性LE的一种不常见但已明确的表现。尽管LE脂膜炎典型地可能累及面部，但据我们所知，此前尚未报道过特定的腮腺及腮腺周围受累情况。我们描述了两例表现为明显原发性腮腺实质疾病的LE脂膜炎病例的临床病理相关性；一例表现为肿瘤，另一例表现为腮腺炎。未能识别LE脂膜炎导致了长时间的不恰当治疗和显著的发病率，包括不必要的腮腺切除术。红斑狼疮脂膜炎有明确的组织学标准，在不明原因腮腺肿块的鉴别诊断中应予以考虑。
