Fraga Javier, García-Díez Amaro
Department of Pathology, Hospital Universitario de La Princesa, Diego de Leon 62, 28006 Madrid, Spain.
Dermatol Clin. 2008 Oct;26(4):453-63, vi. doi: 10.1016/j.det.2008.06.002.
Lupus erythematosus panniculitis is an uncommon variant of lupus erythematosus characterized by a specific involvement of the subcutaneous fat. It is a panniculitis with peculiar clinical features and histopathologically characterized by a mostly lobular panniculitis. It may appear in patients with discoid lupus erythematosus and systemic lupus erythematosus, but also as the unique manifestation of lupus erythematosus, and in the latter cases the diagnosis may be problematic. Histopathologic differential diagnosis with subcutaneous panniculitis-like T-cell lymphoma may also be extremely difficult. This article reviews the salient clinicopathologic features and treatment of lupus erythematosus panniculitis, with special emphasis on the histopathologic features.
红斑狼疮性脂膜炎是红斑狼疮的一种罕见变体，其特征是皮下脂肪受到特定累及。它是一种具有独特临床特征的脂膜炎，组织病理学上主要表现为小叶性脂膜炎。它可能出现在盘状红斑狼疮和系统性红斑狼疮患者中，但也可作为红斑狼疮的唯一表现，在后一种情况下诊断可能存在问题。与皮下脂膜炎样T细胞淋巴瘤的组织病理学鉴别诊断也可能极其困难。本文综述了红斑狼疮性脂膜炎的显著临床病理特征及治疗方法，特别强调了组织病理学特征。
