Berardesca E, Maibach H
Department of Dermatology, University of Pavia, Policlinico S. Matteo, Italy.
Skin Pharmacol. 1993;6(1):3-9.
Transcutaneous gas measurements offer a useful tool for non-invasive monitoring of skin function, but are affected by several variables that restrict their use in clinical and investigative dermatology. Skin thickness, stratum corneum and barrier function damage, blood vessel reactivity, arterial-gas concentration, skin and environmental temperature are important factors influencing transcutaneous gas flux. Improvement of techniques and standardization of methods with guidelines for operators should improve this interesting research approach.
经皮气体测量为皮肤功能的无创监测提供了一种有用的工具，但会受到几个变量的影响，这些变量限制了它们在临床和研究性皮肤病学中的应用。皮肤厚度、角质层和屏障功能损伤、血管反应性、动脉气体浓度、皮肤和环境温度是影响经皮气体通量的重要因素。改进技术并通过为操作人员制定指南使方法标准化，应能改善这种有趣的研究方法。
