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抑制肿瘤生长的电解支架:一项体外及大鼠体内的实验研究

Electrolytic stents to inhibit tumor growth. An experimental study in vitro and in rats.

作者信息

Cwikiel W, Stridbeck H, Stenram U

机构信息

Department of Diagnostic Radiology, University Hospital, Lund, Sweden.

出版信息

Acta Radiol. 1993 May;34(3):258-62.

PMID:8489839
Abstract

Obstruction of metallic stents used in the management of malignant biliary strictures is common and in several cases due to tumor growth through the stent wall. In an experimental animal model in rats, a tumor was implanted subcutaneously adjacent to different metallic stents. Ingrowth of tumor through the wall of these stents was frequent. A stent generating direct electric current on the basis of electrolysis was developed and tested in vitro and in the experimental model. The study confirms that an "electrolytic" stent can inhibit ingrowth of tumor.

摘要

用于治疗恶性胆管狭窄的金属支架阻塞很常见,在某些情况下是由于肿瘤通过支架壁生长所致。在大鼠实验动物模型中,将肿瘤植入不同金属支架附近的皮下。肿瘤通过这些支架壁向内生长很常见。基于电解产生直流电的支架被开发出来并在体外和实验模型中进行了测试。该研究证实,“电解”支架可以抑制肿瘤向内生长。

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