Zaloga G P, Prielipp R C, Butterworth J F, Royster R L
Department of Anesthesia/Critical Care, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
Crit Care Clin. 1993 Apr;9(2):335-62.
The availability of newer and better inotropic agents has led to their widespread application in critically ill medical and surgical patients. Although the elective use of inotropic drugs has been associated with adverse outcomes in patients with cardiomyopathy and chronic heart failure, inotropic drugs used as part of treatment protocols designed to optimize oxygen delivery to tissues have been shown to improve outcome in critical illness. Future research must be aimed toward better definition of clinical settings in which outcome can be improved with inotropes and toward identifying safer agents with fewer adverse side effects.
更新、更好的强心剂的出现促使其在危重症内科和外科患者中广泛应用。尽管在心肌病和慢性心力衰竭患者中选择性使用强心药物与不良结局相关，但作为旨在优化组织氧输送的治疗方案一部分使用的强心药物已被证明可改善危重症的结局。未来的研究必须致力于更明确可通过强心剂改善结局的临床情况，并致力于识别副作用更少的更安全药物。
