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希腊不孕女性中的沙眼衣原体。一项血清学和腹腔镜研究。

Chlamydia trachomatis in infertile Greek women. A serologic and laparoscopic study.

作者信息

Kalogeropoulos A, Frantzidou F, Klearchou N, Diza E, Kyriazopoulou V, Karagiannis V

机构信息

Third Department of Obstetrics and Gynecology, School of Medicine, Aristotelian University of Thessaloniki, Greece.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1993 Feb;48(2):107-10. doi: 10.1016/0028-2243(93)90249-c.

Abstract

This study investigates the prevalence of antichlamydial antibodies in infertile women, who underwent diagnostic laparoscopy. The patients were divided into two groups based on the presence or absence of damage of the fallopian tubes. Antichlamydial IgG antibodies were found in 22 of 27 (81.5%) infertile women with damaged fallopian tubes and 10 of 23 (43.5%) women with normal tubes. Mean geometric IgG titres for C. trachomatis were significantly higher in the patients with damaged tubes (187.4 vs. 39.39). C. trachomatis was not isolated from the peritoneal fluids. Only two chlamydial cultures of cervical specimens were positive, one in each group. These findings confirm that C. trachomatis may be a major cause of tubal damage with resultant infertility.

摘要

本研究调查了接受诊断性腹腔镜检查的不孕女性中抗衣原体抗体的流行情况。根据输卵管是否受损,将患者分为两组。在27名输卵管受损的不孕女性中,有22名(81.5%)检测到抗衣原体IgG抗体;在23名输卵管正常的女性中,有10名(43.5%)检测到该抗体。输卵管受损患者的沙眼衣原体平均几何IgG滴度显著更高(187.4对39.39)。未从腹腔液中分离出沙眼衣原体。宫颈标本的衣原体培养仅2例呈阳性,每组各1例。这些发现证实沙眼衣原体可能是导致输卵管损伤并继而引起不孕的主要原因。

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