Kane J L, Woodland R M, Forsey T, Darougar S, Elder M G
Fertil Steril. 1984 Dec;42(6):843-8. doi: 10.1016/s0015-0282(16)48254-3.
This study investigates the prevalence of Chlamydia trachomatis antibodies in 164 infertile women who underwent diagnostic laparoscopy and dye insufflation as part of routine infertility investigations. C. trachomatis antibodies were found in 36 (22%) of 164 infertile women, which was significantly more than the prevalence of antibodies in a control group (22 of 200, 11%). C. trachomatis antibodies were found in 25 (35.7%) of 70 infertile women who had laparoscopically verified peripheral tubal disease. This was significantly more than the prevalence of C. trachomatis antibodies in infertile women with normal fallopian tubes (6 of 52, 11.5%). The prevalence of C. trachomatis antibodies in infertile patients with laparoscopically verified cornual disease was similar to those without cornual disease. C. trachomatis was not isolated from any of the patients studied. This study confirms that past chlamydial salpingitis is associated with the development of peripheral fallopian tube obstruction with resultant infertility.
本研究调查了164名接受诊断性腹腔镜检查和输卵管通液术（作为常规不孕症检查的一部分）的不孕女性沙眼衣原体抗体的流行情况。在164名不孕女性中，有36名（22%）检测出沙眼衣原体抗体，这显著高于对照组（200名中的22名，11%）抗体的流行率。在70名经腹腔镜检查证实有输卵管周围疾病的不孕女性中，有25名（35.7%）检测出沙眼衣原体抗体。这显著高于输卵管正常的不孕女性中沙眼衣原体抗体的流行率（52名中的6名，11.5%）。经腹腔镜检查证实有子宫角疾病的不孕患者中沙眼衣原体抗体的流行率与无子宫角疾病的患者相似。在所研究的任何患者中均未分离出沙眼衣原体。本研究证实，既往衣原体性输卵管炎与输卵管周围梗阻的发生及由此导致的不孕有关。
