Purnell D C, Scholz D A, Beahrs O H
Arch Surg. 1977 Apr;112(4):369-72. doi: 10.1001/archsurg.1977.01370040021003.
Subtotal parathyroidectomy in all patients with primary hyperparathyroidism has been proposed by several authors. Their data suggest that hyperparathyroidism may recur in up to 30% of patients treated by a conservative operation. This recurrence is attributed to chief-cell hyperplasia as the pathology in one third to one half of all patients. A conservative operation was performed on 198 hyperparathyroid patients with a single enlarged parathyroid gland between 1968 and 1970. Mild elevation of the serum calcium level was noted in two patients three months after operation. Normal serum calcium values were noted each time they were measured in the remaining patients. The present study does not support subtotal parathyroidectomy in all patients with hyperparathyroidism.
几位作者提议对所有原发性甲状旁腺功能亢进患者进行甲状旁腺次全切除术。他们的数据表明，接受保守手术治疗的患者中，高达30%可能会复发甲状旁腺功能亢进。这种复发归因于主细胞增生，在所有患者中有三分之一到一半的病例是这种病理情况。1968年至1970年间，对198例甲状旁腺功能亢进且仅有一个甲状旁腺肿大的患者进行了保守手术。术后三个月，两名患者血清钙水平轻度升高。其余患者每次测量血清钙值均正常。本研究不支持对所有甲状旁腺功能亢进患者进行甲状旁腺次全切除术。
