人体和兔玻璃体疾病的23Na磁共振成像可行性研究。
A feasibility study of 23Na magnetic resonance imaging of human and rabbit vitreal disorders.
作者信息
Kolodny N H, Kohler S J, Rettig E S, Botti P A, D'Amico D J, Gragoudas E S
机构信息
Howe Laboratory of Ophthalmology, Boston, Massachusetts.
出版信息
Invest Ophthalmol Vis Sci. 1993 May;34(6):1917-22.
PURPOSE
To assess the clinical feasibility of sodium magnetic resonance imaging for the visualization and characterization of intraocular tissues.
METHODS
23Na magnetic resonance images were obtained of enucleated human eyes and of rabbit eyes in vivo. The magnetic resonance imaging technique used in this study provided slices of < 2 mm thickness and in-plane resolution of < 2 x 2 mm. From each of these slices local values of spin-spin relaxation time (T2*) were calculated from pixel intensities in each of the eight echoes.
RESULTS
The images clearly display normal anatomic details of the lens and vitreous humor, and important pathologic details such as intravitreal and subretinal hemorrhages, ocular melanoma, and retinal detachments. Intraocular tissue identifications based on relative spin-spin relaxation time values and pixel intensities correlate with those made by standard diagnostic techniques.
CONCLUSIONS
23Na magnetic resonance imaging may be used for the visualization and characterization of intraocular tissues. Differentiation among vitreous humor, lens, aqueous humor, subretinal fluid, or hemorrhage and tumor may be based on image intensity and/or spin-spin relaxation times.
目的
评估钠磁共振成像用于眼内组织可视化及特征描述的临床可行性。
方法
获取了摘除的人眼及兔眼活体的23Na磁共振图像。本研究中使用的磁共振成像技术可提供厚度小于2毫米的切片以及面内分辨率小于2×2毫米的图像。从这些切片中的每一个，根据八个回波中每个像素的强度计算自旋 - 自旋弛豫时间（T2*）的局部值。
结果
图像清晰显示了晶状体和玻璃体的正常解剖细节，以及诸如玻璃体内和视网膜下出血、眼黑色素瘤和视网膜脱离等重要病理细节。基于相对自旋 - 自旋弛豫时间值和像素强度的眼内组织识别与标准诊断技术的识别结果相关。
结论
23Na磁共振成像可用于眼内组织的可视化及特征描述。玻璃体、晶状体、房水、视网膜下液或出血与肿瘤之间的区分可基于图像强度和/或自旋 - 自旋弛豫时间。
Zotero 插件