Kolodny N H, Gragoudas E S, D'Amico D J, Kohler S J, Seddon J M, Murphy E J, Yun C, Albert D M
Howe Laboratory of Ophthalmology, Massachusetts Eye and Ear Infirmary,Boston 02114.
Arch Ophthalmol. 1987 Nov;105(11):1532-6. doi: 10.1001/archopht.1987.01060110078036.
Clinical evaluation of uveal melanomas by magnetic resonance imaging (MRI) techniques depends on developing an understanding of the appearance of these tumors in magnetic resonance (MR) images. We have determined MR characteristics of uveal melanomas by proton (1H) and sodium 23 MRI of freshly enucleated human eyes at 1.5 tesla. The MR images were obtained using two-turn proton and 23Na surface coils, designed to both transmit and receive the radiofrequency signal. Proton MRI techniques included saturation recovery and spin echo; the gradient-recalled echo technique was used for 23Na MRI. Proton and 23Na MR images provide complementary information; contrast between intraocular tumors and vitreous, lens, or subretinal hemorrhage may be varied by using MR pulse sequences that emphasize tissues based on T1, T2, proton, or sodium density values. A combination of proton and 23Na MRI provides differentiation between normal ocular structures and intraocular tumors, as well as associated complications, such as retinal detachments and subretinal hemorrhages.
通过磁共振成像（MRI）技术对葡萄膜黑色素瘤进行临床评估，取决于对这些肿瘤在磁共振（MR）图像中的表现形成理解。我们通过在1.5特斯拉磁场下对新鲜摘除的人眼进行质子（1H）和钠23 MRI，确定了葡萄膜黑色素瘤的MR特征。使用双匝质子和23Na表面线圈获取MR图像，该线圈设计用于发射和接收射频信号。质子MRI技术包括饱和恢复和自旋回波；梯度回波技术用于23Na MRI。质子和23Na MR图像提供互补信息；通过使用基于T1、T2、质子或钠密度值强调组织的MR脉冲序列，眼内肿瘤与玻璃体、晶状体或视网膜下出血之间的对比度可能会有所不同。质子和23Na MRI的结合可区分正常眼结构和眼内肿瘤，以及相关并发症，如视网膜脱离和视网膜下出血。
