François Y, Vignal J, Descos L
Service de Chirurgie Viscérale et Digestive, Hopital Claude Bernard, Centre Hospitalier Lyon-Sud, France.
Int J Colorectal Dis. 1993 Mar;8(1):39-41. doi: 10.1007/BF00341275.
Applying the Hughes' pathogenic classification of ano-perineal lesions of Crohn's disease, this study was conducted to find out its possible prognostic value in perianal fistulas. Thirty-eight patients with ano-perianal fistulas were included; primary specific lesions (condyloma, cavitating ulcer, fissure) were found in 22 patients (group 1) and were absent in the other 16 patients (group 2). Patients of group 1 underwent more abdominal surgical interventions (G 1: 68%; G 2: 31% - P = 0.05), as well as proctological interventions (G 1: 2.95 operations/patient vs 1.35 in G 2 - P = 0.01). Perfect continence was recorded ultimately in 31.8% patients of G 1 compared to 62.5% of G 2. This study shows the very poor prognosis of ano-perianal fistulas in Crohn's disease.
应用休斯对克罗恩病肛门与会阴部病变的致病分类法，开展本研究以探究其在肛周瘘管方面可能的预后价值。纳入了38例肛周瘘管患者；22例患者（第1组）发现有原发性特异性病变（尖锐湿疣、空泡性溃疡、肛裂），另外16例患者（第2组）未发现此类病变。第1组患者接受了更多的腹部外科手术干预（第1组：68%；第2组：31% - P = 0.05），以及直肠科干预（第1组：每位患者2.95次手术，第2组为1.35次 - P = 0.01）。最终记录显示，第1组31.8%的患者实现了完全控便，而第2组为62.5%。本研究表明，克罗恩病肛周瘘管的预后非常差。
