Wechsler Michael E
Pulmonary & Critical Care Division, Harvard Medical School, Brigham & Women's Hospital, 15 Francis Street, Boston, MA 02115, USA.
Immunol Allergy Clin North Am. 2007 Aug;27(3):477-92. doi: 10.1016/j.iac.2007.07.005.
Acute eosinophilic pneumonia, chronic eosinophilia, Churg-Strauss syndrome, and the hypereosinophilic syndrome are pulmonary eosinophilic syndromes characterized by an increased number of eosinophils in peripheral blood, in lung tissue, in sputum, in bronchoalveolar lavage fluid, or in all of these. These pulmonary eosinophilic syndromes generally are characterized by increased respiratory symptoms, abnormal radiographic appearance, and the potential for systemic manifestations. It is critical to exclude other causes of eosinophilia in patients who have lung disease, to make a quick diagnosis, and to treat aggressively with corticosteroids and other therapies to prevent long-term sequelae.
急性嗜酸性粒细胞性肺炎、慢性嗜酸性粒细胞增多症、变应性肉芽肿性血管炎和高嗜酸性粒细胞综合征是肺部嗜酸性粒细胞综合征,其特征是外周血、肺组织、痰液、支气管肺泡灌洗液中或所有这些部位的嗜酸性粒细胞数量增加。这些肺部嗜酸性粒细胞综合征通常表现为呼吸道症状加重、影像学表现异常以及可能出现全身表现。对于患有肺部疾病的患者,排除嗜酸性粒细胞增多的其他原因、快速做出诊断并积极使用皮质类固醇和其他疗法进行治疗以预防长期后遗症至关重要。